The I/OWA Conference announced three speakers today. The speakers are Mike Knoop, co-founder of San Francisco-based Zapier, Karin Brandt, CEO and co-founder of Boston-based coUrbanize, and Greg Isenberg, CEO of Montreal-based 5by. The tech conference will take place on Oct. 10 and 11 at StartupCity Des Moines and the Kirkwood building at 400 Walnut St. Tickets are $50, and can be purchased at www.iowaconf.com. The conference was founded by local startup community leaders to replace the Big Des Moines event canceled recently by Silicon Prairie News.