Fast Company: You don’t have to be one of the world’s largest companies to make an outsized impact. That’s been proved time and again by midsize companies worldwide, and is especially evident for the Brands That Matter 2022 honorees in Fast Company’s midsize category, which recognizes companies with 100 to 999 employees. Some companies grew organically as tastes changed. In today’s food culture, launching a vegan restaurant chain may not seem too daunting. But 15 years ago, Veggie Grill fought an uphill battle to promote plant-based foods. Now, it’s a leader in that space. Other brands reacted to even very timely causes with creative models to support both employees and their greater audience. Bospar, a tech public relations team, paid for the relocation of its Texas staff members after the overturning of Roe v. Wade. Icon, a 3D printing construction company, responded in Nacajuca, Mexico, and other places that desperately needed new structures and homes.